The unravelling stent has been tested in an animal study conducted at St Olavs Hospital Trondheim, Norway. The unravelling stent was inserted in the iliac artery of sheep and left for a period of two weeks before removal. On the contralateral side a traditional permanent stent was inserted for comparison. The segments where the unravelling stent had been placed and the artery together with the traditional stent were collected for histological analysis.
The upper image shows a cross-section of a blood vessel where a knitted stent has been located. The arterial wall is almost normal besides a minimal fraction of scar tissue that is located on the upper wall.
The lower image shows a cross-section with the traditional stent (black dots). It illustrates that scar tissue has formed and narrowed the artery. A blood clot has formed in the centre, which means that the artery has occluded. A phenomenon that did not appear with the unravelling stent.
“The results showing hardly any scar tissue,
intimal hyperplasia with the unraveling stent and classical response with restenos ultimately occlusion with a traditional stent are very thrilling”, says professor Erney Mattsson, co-inventor of the Unravelling Stent and CEO of GraftCraft. “We are now looking at a product that has the possibility to solve a longstanding problem within cardiovascular interventions”